Fast and sensitive bioanalysis using micromachined electrospray interfaces with μ-scale separations
Institute of Analytical Chemistry CAS ·Czechia
About this project
<p>1. Development of micromachined ionization interfaces allowing highly sensitive mass spectrometry analysis of pre-separated biochemical compounds.</p> <p>2. Development of micromachined separation system utilizing the own patented principle of recycling chromatography in which the sample passes repeatedly though the (micro)separation column leading to a significant increase of resolution of its components.</p> <p>3. Development of methodology for coupling of conventional microcolumn-based separation and on-a-chip separation techniques to mass spectrometer through the micromachined interfaces.</p> <p>4. Demonstration of innovation potential of the developed technologies by showcasing two demonstrators targeting high impact applications relevant for life sciences and pharma industries.</p>
Bilateral cooperation results
The bilateral cooperation, mutual research and then the development involved in the project was carried out with a high degree of expertise, professional and meaningful collaboration, and efficiency. The established bilateral cooperation will continue.
Project partners
- SINTEF AS Donor project partner· Norway
- WATREX Praha, s.r.o. Project partner· Czechia